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184 The most prevalent DNA lesions include single-strand breaks (SSBs) and double-strand breaks (DSBs), which are sensed by key damage sensors such as ataxia telangiectasia mutated (ATM), ATM and Rad3-related (ATR), and poly (ADP-ribose) polymerase 1 (PARP1)
Alternative dosing regimens of GLP1 receptor agonists may reduce costs and maintain weight loss efficacy
Oral tirzepatide faces similar bioavailability challenges
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